da Gama A Dinis, Cabral Gonçalo, Ministro Augusto, Evangelista Ana, Damião Angélica, Fernandes Afonso
Clínica Universitária de Cirurgia Vascular e Serviço de Anatomia Patológica do Hospital de Santa Maria, Lisboa.
Rev Port Cir Cardiotorac Vasc. 2009 Apr-Jun;16(2):97-101.
The authors report the clinical case of a 56 years old man who developed a deep venous thrombosis of the left lower extremity, managed conventionally with subcutaneous heparin. Physical examination revealed a large tumor of the middle third, antero lateral view of the left thigh. CT and NMR studies, disclosed an extensive multilobulated tumor along the femoral vessels, with medial deviation of the superficial femoral artery and a surgical biopsy revealed the diagnosis of leiomyosarcoma of the femoral vein, grade 3 of malignancy. The patient underwent a complete resection of the tumor, followed by chemotherapy. Two months after the operation a staging CT scan disclosed multiple micronodular metastasis in both lungs and six months later he was found asymptomatic and in good condition. A review of the literature concerning primary malignant tumors of the veins of the extremities is made, with emphasis on main features of its biology, clinical presentation, methods of diagnosis, treatment and results.