Richards G K, Gagnon R F
Department of Medicine, Montreal General Hospital, McGill University, Canada.
Adv Perit Dial. 1990;6:95-7.
Peritonitis requires a constant focus of infection plus the presence of foreign material, both amply present in the CAPD patient with an indwelling catheter and universal bacterial biofilm. Amazingly the great variety of potentially cytotoxic and immunodiluent agents with which the CAPD peritoneum is confronted on a daily basis does not produce the gross rate of sepsis that might be predicted. Clearly the profound reserve capacity of the peritoneal defense mechanisms, whose functions and interactions are poorly described and understood, contribute to the continuing success of the CAPD modality.
腹膜炎需要持续的感染源加上异物的存在，这在置有留置导管的持续性非卧床腹膜透析（CAPD）患者以及普遍存在的细菌生物膜中都大量存在。令人惊讶的是，CAPD腹膜每天接触的种类繁多的潜在细胞毒性和免疫稀释剂，并未产生可能预测的败血症总发生率。显然，腹膜防御机制具有强大的储备能力，但其功能和相互作用却鲜为人知，这有助于CAPD治疗方式的持续成功。
