Graves病中反对扩展的DR3相关单倍型的证据。
Evidence against extended DR3-related haplotypes in Graves' disease.
作者信息
Weetman A P, McCorkle R
机构信息
Department of Medicine, University of Cambridge Clinical School, Addenbrooke's Hospital, U.K.
出版信息
J Immunogenet. 1990 Dec;17(6):403-7. doi: 10.1111/j.1744-313x.1990.tb00892.x.
Abstract
Three HLA-DR3-linked polymorphisms of the DPA, DPB and DRB genes, previously associated with myasthenia gravis or coeliac disease, have been examined in Caucasian patients with Graves' disease. The patients did not differ from healthy DR3 subjects, indicating an absence of any association of Graves' disease with specific DR3 subtypes.
摘要
在患有格雷夫斯病的白种人患者中，检测了先前与重症肌无力或乳糜泻相关的DPA、DPB和DRB基因的三种HLA - DR3连锁多态性。这些患者与健康的DR3受试者没有差异，表明格雷夫斯病与特定的DR3亚型不存在任何关联。
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