Edwards Max R, Panteliadis Pavlos, Lucas Jonathan D
Department of Spinal Surgery, Guy's and St. Thomas' NHS Trust, Great Maze Pond, London, UK.
J Pediatr Orthop B. 2010 Jan;19(1):95-7. doi: 10.1097/BPB.0b013e32832efca2.
The neuromuscular sequaelae of Guillain-Barré syndrome are well documented in the literature. Persistent distal muscular weakness and loss of peripheral limb reflexes are common in those affected. We report a case of a 14-year-old boy who developed the Miller-Fisher variant of Guillain-Barré syndrome at the age of 8 years. Six years after the acute episode, he had persistent lower limb areflexia and mild weakness. He had also developed a neuromuscular scoliosis. The scoliosis was successfully treated with posterior instrumentation and fusion surgery. Neuromuscular scoliosis is rare following Guillain-Barré syndrome, with no previous reports associated with the Miller-Fisher variant that we are aware of. When evaluating patients post Guillain-Barré syndrome, structural spinal examination is essential to identify rare deformity that may need surgical correction.
格林-巴利综合征的神经肌肉后遗症在文献中有充分记载。持续性远端肌肉无力和外周肢体反射消失在患者中很常见。我们报告一例14岁男孩,他在8岁时患上了格林-巴利综合征的米勒-费雪变异型。急性发作6年后,他仍有持续性下肢反射消失和轻度无力。他还出现了神经肌肉型脊柱侧弯。该脊柱侧弯通过后路器械固定和融合手术得到成功治疗。格林-巴利综合征后出现神经肌肉型脊柱侧弯很罕见,据我们所知,此前没有与米勒-费雪变异型相关的报道。在评估格林-巴利综合征后的患者时,结构性脊柱检查对于识别可能需要手术矫正的罕见畸形至关重要。