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作为吉兰-巴雷综合征后遗症的神经肌肉型脊柱侧弯

Neuromuscular scoliosis as a sequelae of Guillain-Barré syndrome.

作者信息

Edwards Max R, Panteliadis Pavlos, Lucas Jonathan D

机构信息

Department of Spinal Surgery, Guy's and St. Thomas' NHS Trust, Great Maze Pond, London, UK.

出版信息

J Pediatr Orthop B. 2010 Jan;19(1):95-7. doi: 10.1097/BPB.0b013e32832efca2.

DOI:10.1097/BPB.0b013e32832efca2
PMID:19829158
Abstract

The neuromuscular sequaelae of Guillain-Barré syndrome are well documented in the literature. Persistent distal muscular weakness and loss of peripheral limb reflexes are common in those affected. We report a case of a 14-year-old boy who developed the Miller-Fisher variant of Guillain-Barré syndrome at the age of 8 years. Six years after the acute episode, he had persistent lower limb areflexia and mild weakness. He had also developed a neuromuscular scoliosis. The scoliosis was successfully treated with posterior instrumentation and fusion surgery. Neuromuscular scoliosis is rare following Guillain-Barré syndrome, with no previous reports associated with the Miller-Fisher variant that we are aware of. When evaluating patients post Guillain-Barré syndrome, structural spinal examination is essential to identify rare deformity that may need surgical correction.

摘要

格林-巴利综合征的神经肌肉后遗症在文献中有充分记载。持续性远端肌肉无力和外周肢体反射消失在患者中很常见。我们报告一例14岁男孩,他在8岁时患上了格林-巴利综合征的米勒-费雪变异型。急性发作6年后,他仍有持续性下肢反射消失和轻度无力。他还出现了神经肌肉型脊柱侧弯。该脊柱侧弯通过后路器械固定和融合手术得到成功治疗。格林-巴利综合征后出现神经肌肉型脊柱侧弯很罕见,据我们所知,此前没有与米勒-费雪变异型相关的报道。在评估格林-巴利综合征后的患者时,结构性脊柱检查对于识别可能需要手术矫正的罕见畸形至关重要。

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引用本文的文献

1
Successful surgical treatment of scoliosis secondary to Guillain-Barré syndrome: Case report.吉兰-巴雷综合征继发脊柱侧弯的成功手术治疗:病例报告
Medicine (Baltimore). 2016 Jun;95(26):e3775. doi: 10.1097/MD.0000000000003775.
2
Surgical treatment and intraoperative spinal cord monitoring in scoliosis associated with chronic inflammatory demyelinating polyneuropathy: a case report.脊柱侧弯合并慢性炎症性脱髓鞘性多发性神经病的手术治疗及术中脊髓监测:一例报告。
Ups J Med Sci. 2013 May;118(2):134-7. doi: 10.3109/03009734.2012.757682. Epub 2013 Jan 11.