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钛网 cage 间隔物联合经关节螺钉固定治疗类风湿关节炎寰枢椎不稳的疗效与耐久性。

Efficacy and durability of the titanium mesh cage spacer combined with transarticular screw fixation for atlantoaxial instability in rheumatoid arthritis patients.

机构信息

Department of Neurosurgery, Hanyang University Medical Center, Seoul, Korea.

出版信息

Spine (Phila Pa 1976). 2009 Oct 15;34(22):2384-8. doi: 10.1097/BRS.0b013e3181b04f1d.

Abstract

STUDY DESIGN

A retrospective study.

OBJECTIVE

This retrospective investigation was conducted to determine efficacy and endurance of titanium mesh cage as a strut for interlaminar wiring by comparing with autologous iliac bone graft (AIBG). For patients with atlantoaxial instability (AAI), allograft bone was harvested on an interlaminar mesh cage and transarticular fixation (TAF) was performed.

SUMMARY OF BACKGROUND DATA

There have been few studies about atlantoaxial fusion rate and advantages for titanium mesh cage from comparison with AIBG in rheumatoid arthritis (RA) patients.

METHODS

Between January 1998 and October 2007, 55 RA patients were surgically treated for AAI. Among them, 34 patients who underwent surgical treatment with TAF and interlaminar wiring using mesh cage packed with allograft, enrolled in this study (group I). For evaluation of bone fusion about mesh cage group, 21 RA patients who underwent TAF and interlaminar wiring with AIBG were also selected (group II). In both groups, radiologic evidence of bone fusion was assessed with measuring atlantodental interval. Patients were strongly encouraged to mobilize by postoperative 1 day with external cervical bracing. The mean follow-up period was 12.3 months (6-36 months).

RESULTS

Overall, bone fusion was achieved in 33 patients (97%) in group I. And, this was comparable with 100% of group II. There was no statistical difference in bone fusion rate. During the study period, there were 2 instrument-related complications of screw malposition and cable loosening.

CONCLUSION

The results of this study in which mesh cage was used as an interlaminar spacer, showed immediate rigid fixation and successful bone union. We also could prevent donor site morbidities frequently seen in patients with surgical treatment for AAI.

摘要

研究设计

回顾性研究。

目的

通过与自体髂骨移植物(AIBG)比较,评估钛网笼作为椎板间固定物的疗效和耐久性。对于寰枢椎不稳(AAI)患者,在椎间网笼上取同种异体骨,并进行经关节固定(TAF)。

背景资料概述

在类风湿关节炎(RA)患者中,很少有研究比较钛网笼与 AIBG 的寰枢椎融合率和优势。

方法

1998 年 1 月至 2007 年 10 月,55 例 RA 患者接受 AAI 手术治疗。其中,34 例接受 TAF 和椎板间用同种异体骨填充网笼固定的手术治疗患者(I 组)纳入本研究。为评估网笼组的骨融合情况,还选择了 21 例接受 TAF 和椎板间用 AIBG 固定的 RA 患者(II 组)。两组均通过测量寰齿间距评估骨融合情况。术后第 1 天,患者在外部颈托的固定下开始强烈鼓励活动。平均随访时间为 12.3 个月(6-36 个月)。

结果

I 组总体上有 33 例(97%)患者实现了骨融合,与 II 组的 100%相当。两组间骨融合率无统计学差异。研究期间,有 2 例与器械相关的并发症,包括螺钉位置不当和电缆松动。

结论

本研究中使用网笼作为椎板间间隔物,可立即实现刚性固定和成功的骨融合。我们还可以预防在接受 AAI 手术治疗的患者中常见的供体部位并发症。

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