甲基多巴诱发的自身免疫性溶血性贫血再探讨。
Methyldopa-induced autoimmune haemolytic anaemia revisited.
作者信息
Thomas Anish, James Bridget R, Graziano Stephen L
机构信息
Department of Medicine, SUNY Upstate Medical University, Syracuse, NY-13202, USA.
出版信息
N Z Med J. 2009 Aug 21;122(1301):53-6.
Drug-induced haemolytic anaemia is a commonly encountered clinical situation. Methyldopa-induced haemolytic anaemia, once the most common cause of drug induced haemolysis, is now rarely seen due to decline in its use. We report a case of methyldopa induced immune haemolytic anaemia in a young woman where the diagnosis was initially missed. The major mechanisms of drug induced immune haemolysis and unique characteristics of methyldopa induced haemolysis are also outlined.
药物性溶血性贫血是一种常见的临床情况。甲基多巴所致的溶血性贫血曾是药物性溶血最常见的原因，由于其使用减少，现在已很少见。我们报告一例年轻女性甲基多巴所致的免疫性溶血性贫血病例，该病例最初被漏诊。本文还概述了药物性免疫溶血的主要机制以及甲基多巴所致溶血的独特特征。
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