Sakr Rita, Marzouk Paul, Bricou Alexandre, Demaria Fabien, Cortez Annie, Benifla Jean-Louis
Department of Gynecology, Hôpital Armand-Trousseau, 75012 Paris, France and 2Department of Pathology, Hôpital Tenon, 75020 Paris, France.
Cases J. 2009 May 18;2:7515. doi: 10.1186/1757-1626-2-7515.
Uterine adenosarcoma is a rarely observed polypoid tumor with a mixed benign epithelial element and malignant stromal component. The treatment is total hysterectomy with bilateral salpingo-oophorectomy. It could be difficult to diagnose and associated to lymphovascular invasion.
A 45-year-old caucasian uniparous woman presented with uterine bleeding. She had several surgical procedures and pathology of removed recurrent polyps showed no malignancy. Finally, a total abdominal hysterectomy was performed because of atypical cells and suspected uterine adenosarcoma. The hysterectomy specimen confirmed the presence of uterine adenosarcoma associated with lymphatic and vascular tumor emboli. Surgery was completed with a second bilateral salpingo-oophorectomy and pelvic lymphadenectomy.
In our report, we present a case of uterine adenosarcoma which was diagnosed after multiple surgical procedures and associated to lymphovascular emboli known to have a significant impact on overall survival and distant metastasis-free survival.
子宫腺肉瘤是一种罕见的息肉样肿瘤,具有良性上皮成分和恶性间质成分。治疗方法是全子宫切除术加双侧输卵管卵巢切除术。其诊断可能困难,且与淋巴管侵犯有关。
一名45岁的白种单胎女性出现子宫出血。她接受了多次手术,切除的复发性息肉病理检查未显示恶性。最后,由于非典型细胞及疑似子宫腺肉瘤,进行了全腹子宫切除术。子宫切除标本证实存在与淋巴管和血管肿瘤栓子相关的子宫腺肉瘤。手术完成时进行了第二次双侧输卵管卵巢切除术和盆腔淋巴结清扫术。
在我们的报告中,我们呈现了一例子宫腺肉瘤病例,该病例在多次手术后被诊断出来,且与已知对总生存期和无远处转移生存期有重大影响的淋巴管血管栓子有关。