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口服舒马曲坦缓解难治性三叉神经痛:一例报告

Treatment resistant trigeminal neuralgia relieved with oral sumatriptan: a case report.

作者信息

Moran Ja, Neligan A

出版信息

J Med Case Rep. 2009 May 8;3:7229. doi: 10.1186/1752-1947-3-7229.

DOI:10.1186/1752-1947-3-7229
PMID:19830141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2726469/
Abstract

INTRODUCTION

Treatment-resistant trigeminal neuralgia is a distressing condition, for both the patient and the treating doctor. To our knowledge, there are no reported cases of trigeminal neuralgia successfully treated with oral sumatriptan in the literature.

CASE PRESENTATION

A 51-year-old Caucasian woman was prescribed opiate analgesia for management of her treatment-resistant trigeminal neuralgia. Given the possible harmful effects of initiating such a course of treatment, a speculative therapeutic trial with oral sumatriptan was initiated with a successful outcome.

CONCLUSION

This case raises the hypothesis that oral sumatriptan may be an effective drug in the treatment of trigeminal neuralgia. Further research is required to test this theory.

摘要

引言

难治性三叉神经痛对患者和治疗医生来说都是一种痛苦的病症。据我们所知,文献中尚无口服舒马曲坦成功治疗三叉神经痛的报道病例。

病例介绍

一名51岁的白种女性因难治性三叉神经痛而被开具阿片类镇痛药进行治疗。鉴于启动此类治疗过程可能产生的有害影响,遂启动了口服舒马曲坦的探索性治疗试验,结果取得成功。

结论

本病例提出了一种假设,即口服舒马曲坦可能是治疗三叉神经痛的有效药物。需要进一步研究来验证这一理论。

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Sumatriptan alleviates pain in patients with trigeminal neuralgia.舒马曲坦可缓解三叉神经痛患者的疼痛。
Clin J Pain. 2006 Oct;22(8):677-80. doi: 10.1097/01.ajp.0000210917.18536.0d.
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Subcutaneous sumatriptan for refractory trigeminal neuralgia.
Headache. 2006 Apr;46(4):577-82; discussion 583-4. doi: 10.1111/j.1526-4610.2006.00405.x.
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