Pontificia Universidad Católica de Chile, Santiago, Chile.
J Pediatr (Rio J). 2009 Sep-Oct;85(5):455-8. doi: 10.2223/JPED.1927.
To compare the effectiveness of single (1 panel) vs. double (2 panels) phototherapy in reducing nonhemolytic hyperbilirubinemia in term newborns.
Term newborns with hyperbilirubinemia were prospectively randomized to receive double or single phototherapy. Bilirubin levels were measured at admission and at 12-hour intervals, as well as at a follow-up 48 hours after discharge.
Thirty-seven patients received single and 40 double phototherapy. The mean decrease in bilirubin level in the first 24 hours of treatment was greater in the double phototherapy group (5.1+/-2.2 mg/dL vs. 4.3+/-2.1 mg/dL), but without statistical significance (p = 0.18). Readmission rates were similar and no adverse effects were found in either group.
Double-surface was not more effective than single-surface phototherapy in the treatment of nonhemolytic hyperbilirubinemia in term newborns. However, our results suggest that double phototherapy may be more effective in those term newborns with higher bilirubin levels at admission.
比较单(1 个光疗面板)与双(2 个光疗面板)光疗在降低足月新生儿非溶血性高胆红素血症方面的效果。
前瞻性随机分配患有高胆红素血症的足月新生儿接受双光或单光治疗。在入院时以及每 12 小时测量胆红素水平,并在出院后 48 小时进行随访。
37 名患者接受了单光治疗,40 名患者接受了双光治疗。在治疗的前 24 小时内,双光治疗组的胆红素水平下降幅度更大(5.1+/-2.2 mg/dL 比 4.3+/-2.1 mg/dL),但无统计学意义(p = 0.18)。两组的再入院率相似,且均未发现不良反应。
双光治疗在治疗足月新生儿非溶血性高胆红素血症方面并不优于单光治疗。然而,我们的结果表明,对于入院时胆红素水平较高的足月新生儿,双光治疗可能更有效。