亮氨酸丰富的细胞粘附分子（Leu-CAM）和细胞间粘附分子（ICAM）在人类白细胞粘附中的关键作用。
The pivotal role of the Leu-CAM and ICAM molecules in human leukocyte adhesion.
作者信息
Gahmberg C G, Nortamo P, Kantor C, Autero M, Kotovuori P, Hemiö L, Salcedo R, Patarroyo M
机构信息
Department of Biochemistry, University of Helsinki, Finland.
出版信息
Cell Differ Dev. 1990 Dec 2;32(3):239-45. doi: 10.1016/0922-3371(90)90036-v.
Cellular adhesion is of fundamental importance in leukocyte physiology. It is a complex, strictly regulated process, which involves the participation of several cell surface glycoproteins. Among the most important are the Leu-CAMs or the CD11/CD18 integrin receptors, and their adhesion ligands ICAM-1 (CD54) and ICAM-2. In this review we summarize some recent work on various aspects of these molecules.
细胞黏附在白细胞生理学中至关重要。它是一个复杂且受到严格调控的过程，涉及多种细胞表面糖蛋白的参与。其中最重要的是白细胞共同抗原（Leu-CAMs）或CD11/CD18整合素受体，以及它们的黏附配体细胞间黏附分子-1（ICAM-1，CD54）和细胞间黏附分子-2（ICAM-2）。在本综述中，我们总结了关于这些分子各个方面的一些最新研究成果。
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