Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Ocul Immunol Inflamm. 2009 Sep-Oct;17(5):322-4. doi: 10.3109/09273940903043048.
To report a case of intraocular non-Hodgkin lymphoma (NHL) manifesting as persistent intermediate uveitis, facial mass, and Bell palsy.
Retrospective, interventional case report.
A 51-year-old patient with persistent intermediate uveitis for 4 years is diagnosed with intraocular NHL after developing Bell palsy and a facial mass. Initial diagnostic vitrectomy was inconclusive.
Subsequent treatment with cyclophosphamide, adriamycin, vincristine, prednisone, and rituximab resulted in regressed facial mass and improved visual acuity.
NHL can manifest as latent Bell palsy and facial mass in addition to the more common symptoms of uveitis. Intraocular NHL should be suspected in any patient of any age with persistent uveitis.
报告一例以持续性中间葡萄膜炎、面部肿块和贝尔麻痹为表现的眼内非霍奇金淋巴瘤(NHL)。
回顾性、干预性病例报告。
对 1 例 51 岁持续 4 年中间葡萄膜炎的患者,在发生贝尔麻痹和面部肿块后,诊断为眼内 NHL。最初的诊断性玻璃体切除术结果不确定。
随后采用环磷酰胺、阿霉素、长春新碱、泼尼松和利妥昔单抗治疗,面部肿块消退,视力提高。
NHL 除了更常见的葡萄膜炎症状外,还可以表现为潜伏性贝尔麻痹和面部肿块。任何年龄的持续性葡萄膜炎患者都应怀疑眼内 NHL。