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子宫内膜异位症患者的肠易激综合征和慢性便秘。

Irritable bowel syndrome and chronic constipation in patients with endometriosis.

机构信息

Department of Gastroenterology and Hepatology, VU Medical Centre, Amsterdam, the Netherlands.

出版信息

Colorectal Dis. 2011 Jan;13(1):67-71. doi: 10.1111/j.1463-1318.2009.02055.x.

DOI:10.1111/j.1463-1318.2009.02055.x
PMID:19832874
Abstract

AIM

The aim of this study was to evaluate how many patients with endometriosis have concomitant irritable bowel syndrome (IBS) and/or constipation according to the Rome III criteria. Furthermore, the value of an additional gastroenterological consultation with therapeutic advice was evaluated.

METHOD

Patients with proven endometriosis were included in a prospective, single-centre study. A questionnaire was undertaken regarding IBS and chronic constipation. Patients with symptoms consistent with the Rome III criteria for IBS were referred to our gastroenterological outpatient clinic.

RESULTS

In total 101 patients were included. Endometriosis was diagnosed surgically in 97% and visually in the vagina in 3%. Fifteen per cent of the patients with endometriosis also had IBS and 14% of the patients with endometriosis had functional constipation without IBS. Of the 22 patients finally presenting to the gastroenterologist, five had a significant stenotic rectosigmoid lesion and were treated surgically. The remaining 17 patients were treated conservatively. Defecation symptoms improved in 86% and pain was reduced in 64%.

CONCLUSION

In patients with endometriosis, 29% also had IBS or constipation. Referral to a gastroenterologist resulted in improvement of defaecation in 86%, and 64% reported a reduction in the degree of pain.

摘要

目的

本研究旨在评估根据罗马 III 标准,有多少患有子宫内膜异位症的患者同时患有肠易激综合征(IBS)和/或便秘。此外,还评估了额外的胃肠病学咨询和治疗建议的价值。

方法

将患有明确子宫内膜异位症的患者纳入前瞻性单中心研究。通过问卷评估 IBS 和慢性便秘。符合 IBS 罗马 III 标准的患者被转介至我们的胃肠病门诊。

结果

共纳入 101 例患者。97%的患者通过手术、3%的患者通过阴道镜检查确诊为子宫内膜异位症。15%的子宫内膜异位症患者同时患有 IBS,14%的子宫内膜异位症患者患有功能性便秘而无 IBS。最终有 22 例患者就诊于胃肠病学家,其中 5 例存在明显狭窄的直肠乙状结肠病变并接受了手术治疗。其余 17 例患者接受了保守治疗。86%的患者排便症状改善,64%的患者疼痛减轻。

结论

在患有子宫内膜异位症的患者中,29%同时患有 IBS 或便秘。将患者转介至胃肠病学家后,86%的患者排便改善,64%的患者疼痛程度减轻。

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