新型对称和不对称呫吨染料的一锅法合成
One-Pot Synthesis of New Symmetric and Asymmetric Xanthene Dyes.
作者信息
Hilderbrand Scott A, Weissleder Ralph
机构信息
Center for Molecular Imaging Research, Massachusetts General Hospital/Harvard Medical School, Charlestown, Massachusetts 02129, USA.
出版信息
Tetrahedron Lett. 2007 Jun 18;48(25):4383-4385. doi: 10.1016/j.tetlet.2007.04.088.
Abstract
Symmetric and asymmetric xanthene dyes have been prepared by a convenient one-step procedure from aldehyde and diol or m-aminophenol precursors using concentrated phosphoric acid as a solvent. This protocol provides access to water-soluble dyes with large Stoke's shifts and far-red fluorescence emission. These compounds are envisioned as components of fluorescence-based sensors for a variety of imaging applications.
摘要
对称和不对称呫吨染料已通过一种简便的一步法由醛和二醇或间氨基酚前体使用浓磷酸作为溶剂制备而成。该方案可制备出具有大斯托克斯位移和远红色荧光发射的水溶性染料。这些化合物被设想为用于各种成像应用的基于荧光的传感器的组件。
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