Bertolino Chiara A, Caputo Giuseppe, Barolo Claudia, Viscardi Guido, Coluccia Salvatore
Dipartimento di Chimica IFM, Università di Torino, Italy.
J Fluoresc. 2006 Mar;16(2):221-5. doi: 10.1007/s10895-006-0094-8.
A series of novel functionalized, water-soluble, pH-unsensitive, highly photostable heptamethine cyanine dyes (HCDs) has been synthesized. The aim of the synthesis was to obtain novel effective probes for fluorescence detection in the near infrared. Synthesis and characterization of a special HCD with large Stokes' shift (>100 nm), bioconjugation to IgG and effect of pH upon the new structure are presented.
已经合成了一系列新型的功能化、水溶性、pH不敏感、高光稳定性的七甲川花菁染料（HCDs）。合成的目的是获得用于近红外荧光检测的新型有效探针。介绍了一种具有大斯托克斯位移（>100 nm）的特殊HCD的合成与表征、与IgG的生物共轭以及pH对新结构的影响。
