Schultheiss H-P, Lassner D, Kühl U
Medizinische Klinik II, Kardiology und Pneumonology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin.
Dtsch Med Wochenschr. 2009 Oct;134 Suppl 6:S195-7. doi: 10.1055/s-0029-1241907. Epub 2009 Oct 15.
Distinct examinations and resulting therapies are depending on the cardiomyopathy phenotype and the severity of the myocardial compromise. Specific treatment modalities for distinct cardiomyopathies, demand detailed diagnostic procedures in addition to the routine diagnostic workup. Quality analyses for causal treatment strategies of different cardiomyopathies are missing. Most diagnostic procedures are unable to detect the relevant pathophysiological changes that generally occur at the cellular and molecular level of myocardial tissue or individual cells. Therefore, often only additional biopsy-based tissue analyses can provide the necessary basis for causal treatment options.
不同的检查及相应的治疗方法取决于心肌病的表型和心肌损害的严重程度。对于不同的心肌病,特定的治疗方式除了常规诊断检查外,还需要详细的诊断程序。目前缺少针对不同心肌病因果治疗策略的质量分析。大多数诊断程序无法检测到通常在心肌组织或单个细胞的细胞和分子水平上发生的相关病理生理变化。因此,通常只有额外的基于活检的组织分析才能为因果治疗方案提供必要的依据。