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[以低分子量肝素作为唯一药物和/或联合二氢麦角胺预防血栓形成:临床研究结果]

[Prevention of thrombosis with low molecular weight heparin as the only substance and/or with DHE: results of clinical studies].

作者信息

Koppenhagen K, Tröster E, Matthes M, Häring R

机构信息

Klinikum Steglitz FU Berlin.

出版信息

Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990:1163-6.

PMID:1983504
Abstract

In aspect of the high incidence of thrombosis and the resulting risk of fulminant pulmonary embolism and late complications, there is a demand for a general medical prophylaxis in operative medicine. A new chance to reduce the incidence of thrombosis is the recently developed low weight molecular heparine (LWMH). Current studies of different LWMH in general and thoracic surgery prove, that an effective decrease of thrombosis can be achieved with a single daily injection. Effectiveness of LWMH in high risk patients have not been sufficient evaluated yet in some of the used preparations.

摘要

鉴于血栓形成的高发生率以及由此导致的暴发性肺栓塞和晚期并发症的风险,手术医学中需要一种通用的医学预防措施。最近开发的低分子量肝素(LWMH)为降低血栓形成的发生率提供了新的契机。目前关于不同低分子量肝素在普通外科和胸外科的研究表明,每日单次注射即可有效降低血栓形成的发生率。某些已使用的制剂中,低分子量肝素在高危患者中的有效性尚未得到充分评估。

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