西班牙格拉纳达家庭医生放置 372 枚依托孕烯皮下埋植剂的经验：插入及 3 年随访。
Insertion and 3-year follow-up experience of 372 etonogestrel subdermal contraceptive implants by family physicians in Granada, Spain.
机构信息
University Health Centre of La Chana, Health District of Granada, Andalusian Health Service, Granada 18015, Spain.
出版信息
Contraception. 2009 Nov;80(5):457-62. doi: 10.1016/j.contraception.2009.04.003. Epub 2009 May 14.
BACKGROUND
User profile, continuation rate, reasons for discontinuation, problems during insertion and removal, and effectiveness of an etonogestrel subdermal contraceptive implant (ESCI) were assessed.
STUDY DESIGN
A follow-up of 372 women 3 years after insertion of an ESCI performed by family physicians in Granada, Spain, by means of consultations, examination of medical records and telephone interviews.
RESULTS
Data were available for 356 (95.7%) women. The average age was 27.2 years, and 159 (42.7%) were nulliparous. Continuation rates were 91.0% at 1 year, 74.7% at 2 years and 65.1% at 2 years and 9 months. The main reasons for discontinuation were excessive bleeding (44, 12.4%), wish to become pregnant (44, 12.4%) and side effects not related to menstruation (21, 5.9%). However, 141 (39.6%) received a second implant when the first one expired. No pregnancy occurred in 893.4 women-years.
CONCLUSIONS
Family physicians can achieve excellent results with the ESCI. It should be included in the range of contraceptives offered by primary care physicians.
背景
评估了用户档案、续用率、停药原因、插入和取出过程中的问题以及依托孕诺酮皮下埋植避孕剂（依托孕诺酮埋植剂）的有效性。
研究设计
对西班牙格拉纳达的家庭医生为 372 名女性进行依托孕诺酮埋植剂植入 3 年后的随访，通过咨询、查阅病历和电话访谈进行。
结果
356 名（95.7%）女性的数据可用。平均年龄为 27.2 岁，159 名（42.7%）为未产妇。1 年时的续用率为 91.0%，2 年时为 74.7%，2 年 9 个月时为 65.1%。停药的主要原因是出血过多（44 例，12.4%）、希望怀孕（44 例，12.4%）和与月经无关的副作用（21 例，5.9%）。然而，当第一个埋植剂到期时，有 141 名（39.6%）女性接受了第二个埋植剂。893.4 名妇女-年无妊娠发生。
结论
家庭医生可以用依托孕诺酮埋植剂取得很好的效果。它应该被纳入初级保健医生提供的避孕方法范围。
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