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依托孕烯避孕植入剂(依伴侬):哺乳期患者依从性及不良反应分析

Etonogestrel contraceptive implant (Implanon): analysis of patient compliance and adverse effects in the breastfeeding period.

作者信息

Duvan Candan İltemir, Gözdemir Elif, Kaygusuz Ikbal, Kamalak Zeynep, Turhan Nilgün Öztürk

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Fatih University, Ankara, Turkey.

出版信息

J Turk Ger Gynecol Assoc. 2010 Sep 1;11(3):141-4. doi: 10.5152/jtgga.2010.21. eCollection 2010.

Abstract

OBJECTIVE

To analyse the compliance of patients and side effects of Implanon® during breast feeding.

MATERIAL AND METHODS

Prospective study of 61 postpartum women who chose Implanon® for long term contraception between April 2007 and December 2009. Compliance, side effects and removals were recorded.

RESULTS

Amenorrhoea, prolonged bleeding, frequent bleeding and infrequent bleeding were reported in 20 (32%), 13 (21%), 4 (6.5%) and 2 (3.2%) patients, respectively. Non-menstrual side effects experienced by participants included; weight gain reported by 10 patients (16%), anxiety by 6 (9.8%), breast tenderness by 4 (6.5%), headache by 4 (6.5%), pain at the insertion site by two (3.2%), hirstutism by two (3.2%), acne by 1 (1.6%), loss of libido by 1 (1.6%), weight gain and headache by two (3.2%), weight gain and anxiety by two (1.6%). The mean breastfeeding period was 16±7.4/months. During the follow up, Implanon® was removed from 24 patients (39%).

CONCLUSION

If patients are well informed about its expected side effects before placement, Implanon® is well tolerated and i an acceptable choice for women who have recently experienced labor and are looking for long term reversible contraception.

摘要

目的

分析哺乳期妇女使用依伴侬(Implanon®)的依从性及副作用。

材料与方法

对2007年4月至2009年12月间选择依伴侬进行长期避孕的61名产后妇女进行前瞻性研究。记录依从性、副作用及取出情况。

结果

分别有20名(32%)、13名(21%)、4名(6.5%)和2名(3.2%)患者报告出现闭经、经期延长、频繁出血和偶发出血。参与者经历的非月经副作用包括:10名患者(16%)报告体重增加,6名(9.8%)焦虑,4名(6.5%)乳房胀痛,4名(6.5%)头痛,2名(3.2%)植入部位疼痛,2名(3.2%)多毛,1名(1.6%)痤疮,1名(1.6%)性欲减退,2名(3.2%)体重增加和头痛,2名(1.6%)体重增加和焦虑。平均哺乳期为16±7.4个月。随访期间,24名患者(39%)取出了依伴侬。

结论

如果在植入前让患者充分了解其预期副作用,依伴侬耐受性良好,对于近期分娩且寻求长期可逆避孕的女性来说是一个可接受的选择。

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