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[亚急性动脉闭塞中的全身溶解]

[Systemic lysis in subacute arterial occlusion].

作者信息

Martin M, Fiebach B J

机构信息

Geriatrische Klinik, Städtische Kliniken, Duisburg.

出版信息

Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990:417-20.

PMID:1983582
Abstract

The therapeutic regimen used consisted of an ultrahigh streptokinase dosage scheme with an infusion rate of 1.5 million units per hour over a period of 6 hours. Where no immediate clearance occurred or where residual stenoses persisted, a catheter dilation (PTA) was subsequently carried out. Favorable results were achieved in the group of up to 6 week old femoral occlusions with 2 or 3 calf arteries open and an occlusion length below 15 cm. Iliac occlusions responded well to lytic treatment if a 3 month history was not exceeded.

摘要

所采用的治疗方案包括超高剂量链激酶给药方案,即每小时输注150万单位,持续6小时。若未立即出现血管再通或仍存在残余狭窄,则随后进行导管扩张术(经皮腔内血管成形术)。对于年龄在6周及以下、有2或3条小腿动脉通畅且闭塞长度小于15 cm的股动脉闭塞患者,治疗效果良好。如果髂动脉闭塞病史不超过3个月,溶栓治疗效果良好。

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