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[宫颈狭窄和/或闭锁情况下的胚胎移植]

[Embryo transfer in case of stenosed and/or forbidding cervix].

作者信息

Ohl J

机构信息

AMP clinique, CMCO-SIHCUS, 19, rue Louis-Pasteur, 67300 Schiltigheim, France.

出版信息

Gynecol Obstet Fertil. 2009 Nov-Dec;37(11-12):890-4. doi: 10.1016/j.gyobfe.2009.09.008.

DOI:10.1016/j.gyobfe.2009.09.008
PMID:19836286
Abstract

A cervical stenosis can follow an infection, a conisation or a trachelectomy and lead to a cervical infertility. In in vitro fertilization (IVF), embryo transfers are difficult in case of a cervical stenosis and specific care is required. Treatments try to restore an adequate cervical patency. Repeated cervical dilatations can represent a solution. In case of inefficiency, a new cervicoisthmic opening has to be created with surgery. Perpetuity of the result is obtained thanks to post surgical dilatations or thanks to implementation of an intracervical catheter till complete cicatrization. In case of failure of canalization of the stenosed isthmic os, alternative treatments can be proposed. Intraperitoneal insemination in the poutch of Douglas is interesting when tubes are patent and when semen quality is sufficient. On the contrary, transmyometrial embryo transfer and gametes or zygotes intrafallopian transfer represent an ultimate therapeutic option.

摘要

宫颈狭窄可能继发于感染、锥形切除术或宫颈切除术,并导致宫颈性不孕。在体外受精(IVF)中,宫颈狭窄时胚胎移植困难,需要特殊护理。治疗旨在恢复宫颈的通畅。反复宫颈扩张可能是一种解决办法。如果无效,则必须通过手术创建新的宫颈峡部开口。通过术后扩张或通过放置宫颈内导管直至完全愈合可维持手术效果。如果狭窄的峡部口插管失败,可以考虑其他治疗方法。当输卵管通畅且精液质量足够时,在Douglas陷凹进行腹腔内授精是可行的。相反,经子宫肌层胚胎移植以及配子或受精卵输卵管内移植是最终的治疗选择。

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[Embryo transfer in case of stenosed and/or forbidding cervix].[宫颈狭窄和/或闭锁情况下的胚胎移植]
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[Congenital cervical agenesis: pregnancy after transmyometrial embryo transfer].[先天性宫颈闭锁:经子宫肌层胚胎移植后的妊娠]
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Relationship of cytopathology and cervical infection to outcome of in-vitro fertilization and embryo transfer.细胞病理学及宫颈感染与体外受精和胚胎移植结局的关系。
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引用本文的文献

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Transmyometrial embryo transfer as a useful method to overcome difficult embryo transfers - a single-center retrospective study.经子宫肌层胚胎移植作为克服困难胚胎移植的一种有效方法——一项单中心回顾性研究
JBRA Assist Reprod. 2018 Jun 1;22(2):134-138. doi: 10.5935/1518-0557.20180029.
2
Comparison of easy and difficult embryo transfer outcomes in in vitro fertilization cycles.体外受精周期中难易程度不同的胚胎移植结果比较。
Int J Fertil Steril. 2013 Jan;6(4):232-7. Epub 2013 Mar 3.
3
Fertility-preserving surgery in patients with early stage cervical carcinoma.早期宫颈癌患者的保留生育功能手术。
ISRN Oncol. 2012;2012:817065. doi: 10.5402/2012/817065. Epub 2012 Dec 18.
4
Use of Versapoint to refashion the cervical canal to overcome unusually difficult embryo transfers and improve in-vitro fertilization-embryo transfer outcome: A case series.使用Versapoint重塑宫颈管以克服异常困难的胚胎移植并改善体外受精-胚胎移植结局:病例系列
J Hum Reprod Sci. 2011 Jan;4(1):12-6. doi: 10.4103/0974-1208.82353.