Wandoloski Melissa, Bussey Kimberly J, Demeure Michael J
Translational Genomics Research Institute, Clinical Translational Research Division, Phoenix, AZ 85004, USA.
Surg Clin North Am. 2009 Oct;89(5):1255-67. doi: 10.1016/j.suc.2009.06.019.
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy causing up to 0.2% of all cancer deaths This article reviews the incidence, presentation, and pathology of ACC. Particular attention is paid to the molecular oncogenesis of this disease, and the surgical and therapeutic options available for its cure.
肾上腺皮质癌(ACC)是一种罕见的内分泌恶性肿瘤,在所有癌症死亡病例中占比高达0.2%。本文综述了肾上腺皮质癌的发病率、临床表现及病理特征。特别关注了该疾病的分子肿瘤发生机制,以及可用于治愈该病的手术和治疗选择。