Department of Neurology, Faculty of Medicine, Adana Hospital, Baskent University, Dadaloglu Mah. 39. Sk. No: 6, 01250 Yüregir, Adana, Turkey.
J Clin Neurosci. 2009 Dec;16(12):1582-7. doi: 10.1016/j.jocn.2009.03.028. Epub 2009 Oct 17.
The aim of this study was to measure the health related quality of life (HRQOL) of epilepsy patients and to compare it with that of a healthy control group. The evaluation included the effects of the type of seizure, duration of seizure and medical treatment on the quality of life of the patients. The group studied consisted of 221 participants (121 epilepsy patients and 100 healthy control individuals) who completed a sociodemographic data form and who were administered the World Health Organization Quality of Life (WHOQOL-100) scale. The epilepsy patients had statistically lower physical health, psychological well-being, level of independence and global HRQOL than participants in the control group (p<0.05). The analysis of variance showed that the partial epilepsy subgroup had significantly lower averages for all the quality-of-life subfields except for the social relationship dimension. On regression analysis, being married, having a generalized type of seizure and being treated with fewer medications were all related to higher scores on the HRQOL. Epilepsy is a disease that has neurological, psychiatric and psychosocial dimensions that should be evaluated using a multidisciplinary approach.
本研究旨在测量癫痫患者的健康相关生活质量(HRQOL),并将其与健康对照组进行比较。评估包括癫痫发作类型、发作持续时间和药物治疗对患者生活质量的影响。研究组由 221 名参与者(121 名癫痫患者和 100 名健康对照组)组成,他们完成了一份社会人口统计学数据表格,并接受了世界卫生组织生活质量(WHOQOL-100)量表的评估。与对照组相比,癫痫患者的身体健康、心理健康、独立性水平和整体 HRQOL 均明显较低(p<0.05)。方差分析显示,部分癫痫亚组在除社会关系维度外的所有生活质量子领域的平均值均显著较低。在回归分析中,已婚、全身性发作和服用较少药物治疗均与 HRQOL 得分较高相关。癫痫是一种具有神经、精神和心理社会维度的疾病,应采用多学科方法进行评估。