升汞实验性中毒动物尿液和血液中几种酶的活性。第二部分。慢性中毒。
The activity of several enzymes in the urine and blood of animals in experimental poisoning with sublimate. Part. II. Chronic poisoning.
作者信息
Starnawska M, Hać E
机构信息
Clinic of Occupational and Tropical Diseases, Institute of Maritime and Tropical Medicine, Gdynia.
出版信息
Bull Inst Marit Trop Med Gdynia. 1990;41(1-4):89-96.
Fourteen guinea pigs were injected with sublimate during the period of 3 months. Their urine and blood was examined. In the urine an increase of activity of alkaline phosphatase and lactate dehydrogenase was noted. In the blood plasma an increase of lactate dehydrogenase activity was observed and in the blood serum decrease of gamma-glutamyl-transpeptidase activity. The determination of alkaline phosphatase in urine is a sensitive indicator of renal damage caused by mercury. It has a greater diagnostic value than the determination of this enzyme in the blood serum.
在3个月的时间里，给14只豚鼠注射了升汞。对它们的尿液和血液进行了检查。发现尿液中碱性磷酸酶和乳酸脱氢酶的活性增加。血浆中观察到乳酸脱氢酶活性增加，血清中γ-谷氨酰转肽酶活性降低。尿液中碱性磷酸酶的测定是汞引起肾损伤的敏感指标。它比血清中该酶的测定具有更大的诊断价值。
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