Department of Surgery, Division of Vascular and Transplant Surgery, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
J Endovasc Ther. 2009 Oct;16(5):546-51. doi: 10.1583/09-2775.1.
To quantify dynamic changes in aortoiliac dimensions using dynamic electrocardiographically (ECG)-gated computed tomographic angiography (CTA) and to investigate any potential impact on preoperative endograft sizing in relation to observer variability.
Dynamic ECG-gated CTA was performed in 18 patients with abdominal aortic aneurysms. Postprocessing resulted in 11 datasets per patient: 1 static CTA and 10 dynamic CTA series. Vessel diameter, length, and angulation were measured for all phases of the cardiac cycle. The differences between diastolic and systolic aneurysm dimensions were analyzed for significance using paired t tests. To assess intraobserver variability, 20 randomly selected datasets were analyzed twice. Intraobserver repeatability coefficients (RC) were calculated using Bland-Altman analysis.
Mean aortic diameter at the proximal neck was 21.4+/-3.0 mm at diastole and 23.2+/-2.9 mm at systole, a mean increase of 1.8+/-0.4 mm (8.5%, p<0.01). The RC for the aortic diameter at the level of the proximal aneurysm neck was 1.9 mm (8.9%). At the distal sealing zones, the mean increase in diameter was 1.7+/-0.3 mm (14.1%, p<0.01) for the right and 1.8+/-0.5 mm (14.2%, p<0.01) for the left common iliac artery (CIA). At both distal sealing zones, the mean increase in CIA diameter exceeded the RC (10.0% for the right CIA and 12.6% for the left CIA).
The observed changes in aneurysm dimension during the cardiac cycle are small and in the range of intraobserver variability, so dynamic changes in proximal aneurysm neck diameter and aneurysm length likely have little impact on preoperative endograft selection. However, changes in diameter at the distal sealing zones may be relevant to sizing, so distal oversizing of up to 20% should be considered to prevent distal type I endoleak.
使用动态心电图门控计算机断层血管造影(CTA)定量主动脉-髂动脉的尺寸变化,并研究观察者变异性对术前内支架选择的潜在影响。
对 18 例腹主动脉瘤患者进行了动态心电图门控 CTA。每位患者产生 11 个数据集:1 个静态 CTA 和 10 个动态 CTA 系列。在心动周期的所有阶段测量血管直径、长度和角度。使用配对 t 检验分析舒张期和收缩期动脉瘤尺寸之间的差异是否有统计学意义。为了评估观察者内变异性,随机选择 20 个数据集进行两次分析。使用 Bland-Altman 分析计算观察者内重复性系数(RC)。
近端颈部主动脉直径在舒张期为 21.4±3.0mm,在收缩期为 23.2±2.9mm,平均增加 1.8±0.4mm(8.5%,p<0.01)。近端动脉瘤颈部水平的主动脉直径 RC 为 1.9mm(8.9%)。在远端密封区,右侧直径平均增加 1.7±0.3mm(14.1%,p<0.01),左侧直径平均增加 1.8±0.5mm(14.2%,p<0.01)。在两个远端密封区,髂总动脉直径的平均增加均超过 RC(右侧髂总动脉为 10.0%,左侧髂总动脉为 12.6%)。
在心动周期中观察到的动脉瘤尺寸变化较小,且处于观察者内变异性范围内,因此近端动脉瘤颈部直径和动脉瘤长度的动态变化可能对术前内支架选择影响不大。然而,远端密封区的直径变化可能与尺寸有关,因此应考虑远端过度扩张 20%,以防止远端 I 型内漏。