Department of Chemistry, The Scripps Research Institute, 10550 N, Torrey Pines Road, La Jolla, CA 92037, USA.
Chem Soc Rev. 2009 Nov;38(11):3010-21. doi: 10.1039/b821200g. Epub 2009 Aug 21.
In this tutorial review the economies of synthesis are analysed from both detailed and macroscopic perspectives, using case-studies from complex molecule synthesis. Atom, step, and redox economy are more than philosophical constructs, but rather guidelines, which enable the synthetic chemist to design and execute an efficient synthesis. Students entering the field of synthesis might find this tutorial helpful for understanding the subtle differences between these economic principles and also see real-world situations where such principles are put into practice.
在本教程中，我们从详细和宏观的角度分析了合成的经济性，使用了来自复杂分子合成的案例研究。原子经济性、步骤经济性和氧化还原经济性不仅仅是哲学概念，而是指导原则，使合成化学家能够设计和执行有效的合成。进入合成领域的学生可能会发现本教程有助于理解这些经济原则之间的细微差别，并看到实际应用这些原则的情况。
