Warnecke I C, Raute-Kreinsen U, Schirmer S, Kretschmer F, Fansa H
Klinikum Bielefeld Mitte, Klinik für Plastische, Rekonstruktive und Asthetische Chirurgie, Handchirurgie, Bielefeld.
Handchir Mikrochir Plast Chir. 2010 Aug;42(4):260-2. doi: 10.1055/s-0029-1238310. Epub 2009 Oct 21.
The purple glove syndrome (PGS) is a soft tissue injury after peripheral intravenous phenytoin administration or oral overdosage. The incidence of PGS is described with 0-6%. Typical symptoms are purple discoloration, oedema, pain, and a decrease of range of motion. In severe cases PGS may lead to abscess, skin loss and compartment syndrome. The established treatment of PGS is immediate interruption of phenytoin injections, splinting, elevation, and close observation. In cases of severe complications (e. g., compartment syndrome), surgical intervention is necessary. The case of a 40-year-old female patient is reported who was transferred to our department 4 days after intravenous phenytoin administration and who underwent successful surgical revision.
紫手套综合征(PGS)是外周静脉注射苯妥英或口服过量后发生的软组织损伤。PGS的发生率为0%-6%。典型症状为皮肤发紫、水肿、疼痛和活动范围减小。严重的PGS病例可能导致脓肿、皮肤缺损和骨筋膜室综合征。PGS的既定治疗方法是立即停止苯妥英注射、夹板固定、抬高患肢并密切观察。对于严重并发症(如骨筋膜室综合征)的病例,手术干预是必要的。本文报道了一名40岁女性患者的病例,该患者在静脉注射苯妥英4天后转入我科,并成功接受了手术翻修。