Gamaly Tamer
Magrabi Eye & Ear Center, Muscat, Oman.
J Refract Surg. 2009 Oct;25(10 Suppl):S927-30. doi: 10.3928/1081597X-20090915-05.
The predictability and safety of LASIK with the optimized aspheric transition zone (OATz) and cross-cylinder technique were evaluated for the surgical correction of myopia with 1.00 to 4.25 diopters (D) of astigmatism.
In this prospective study, 74 eyes of 48 consecutive LASIK patients with astigmatism ranging from 1.00 to 4.25 D were evaluated. All eyes underwent laser ablation with profile 7 of the OATz algorithm with the NIDEK CXIII excimer laser platform. Refractive outcomes, visual acuity, and patient satisfaction were assessed based on 6-month postoperative data.
Preoperative manifest refraction spherical equivalent (MRSE) was -2.10+/-1.19 D (range: -0.50 to -5.75 D) and mean cylinder was -1.94+/-0.89 D (range: -1.00 to -4.25 D). At 6 months postoperatively, the mean MRSE for all eyes was 0.01+/-0.37 D (range: -0.75 to +1.00 D). Postoperatively, 78.3% (58/74) of eyes achieved uncorrected visual acuity (UCVA) of 20/20 or better, and 97.3% (72/74) of eyes achieved UCVA of 20/40 or better. Regarding predictability, 94.6% (70/74) of eyes were within +/-0.50 D of intended MRSE and 98.6% (73/74) of eyes were within +/-1.00 D of intended MRSE. Four (5.3%) eyes lost two lines of best spectacle-corrected visual acuity at 6 months. Stability was reached between 1 and 3 months and verified at 6 months postoperatively.
LASIK with OATz and the cross-cylinder technique is safe and predictable for the treatment of patients with astigmatism up to 4.25 D.
评估采用优化非球面过渡区（OATz）和交叉柱镜技术的准分子原位角膜磨镶术（LASIK）治疗散光度数在1.00至4.25屈光度（D）之间的近视患者的可预测性和安全性。
在这项前瞻性研究中，对48例连续接受LASIK手术的散光患者的74只眼睛进行了评估，散光度数范围为1.00至4.25 D。所有眼睛均使用NIDEK CXIII准分子激光平台，采用OATz算法的7号模式进行激光消融。根据术后6个月的数据评估屈光结果、视力和患者满意度。
术前明显屈光不正球镜等效值（MRSE）为-2.10±1.19 D（范围：-0.50至-5.75 D），平均柱镜度数为-1.94±0.89 D（范围：-1.00至-4.25 D）。术后6个月，所有眼睛的平均MRSE为0.01±0.37 D（范围：-0.75至+1.00 D）。术后，78.3%（58/74）的眼睛裸眼视力（UCVA）达到20/20或更好，97.3%（72/74）的眼睛UCVA达到20/40或更好。关于可预测性，94.6%（70/74）的眼睛屈光度数在预期MRSE的±0.50 D范围内，98.6%（73/74）的眼睛屈光度数在预期MRSE的±1.00 D范围内。4只（5.3%）眼睛在术后6个月最佳矫正视力下降了两行。在术后1至3个月达到稳定，并在术后6个月得到验证。
采用OATz和交叉柱镜技术的LASIK治疗散光度数高达4.25 D的患者是安全且可预测的。
