骨髓转移性默克尔细胞癌的细胞遗传学研究

Cytogenetic study in a bone marrow metastatic Merkel cell carcinoma.

作者信息

Smadja N, de Gramont A, Gonzalez-Canali G, Louvet C, Wattel E, Krulik M

机构信息

Laboratoire de Recherche en Cytogénétique Hémato-Cancérologique, Hôpital Saint-Antoine, Paris, France.

出版信息

Cancer Genet Cytogenet. 1991 Jan;51(1):85-7. doi: 10.1016/0165-4608(91)90013-k.

DOI:10.1016/0165-4608(91)90013-k

PMID:1984852

Abstract

We report an additional cytogenetic study of a metastatic Merkel cell carcinoma. Even though the cells analyzed were from a metastatic lesion, chromosomal abnormalities were not complex. Similarities between cytogenetic findings described in small-cell lung carcinoma and the present case are observed. However, further studies are needed to define the relationship between these two neuroendocrine small-cell malignancies.

摘要

我们报告了一例转移性默克尔细胞癌的额外细胞遗传学研究。尽管分析的细胞来自转移病灶，但染色体异常并不复杂。观察到小细胞肺癌中描述的细胞遗传学发现与本病例之间存在相似性。然而，需要进一步研究来确定这两种神经内分泌小细胞恶性肿瘤之间的关系。