Tinoco Renam C, Tinoco Augusto C A, El-Kadre Luciana J, Sueth Daniela M, Conde Lauro M
Department of Surgery, Hospital São José do Avaí, Brazil.
Surg Laparosc Endosc Percutan Tech. 2009 Oct;19(5):384-7. doi: 10.1097/SLE.0b013e3181ba4701.
Surgery in gastric cancer (GC) aims to achieve resection of the primary tumor and its lymphatic drain, with a minimal adverse effect on morbidity and mortality, and the best possible quality of life.
From June 1993 to May 2008, 113 patients with a preoperative diagnosis of the GC were considered for laparoscopic gastrectomy at our institution. There was a predominance of males and mean age was 60 years. After peritoneal cavity inspection, laparoscopic ultrasound was used to determine the presence of deep liver metastasis. Total gastrectomy and Roux-en-Y reconstruction were performed in upper and middle-third tumors, and subtotal gastrectomy, either with Billroth II or Roux-en-Y reconstruction, in tumors affecting the lower third of the stomach. D2 lymphadenectomy was performed in both cases.
There were 21 cases (18.5%) with distant metastases and/or an unresectable tumor due to the invasion of adjacent organs. In these patients the procedure was limited to laparoscopic biopsy in 16 cases and laparoscopic gastrojejunostomy in 5 cases. Laparoscopic gastrectomy was performed in 92 patients with a mean surgical time of 162 minutes and a mortality rate of 5.4%. Conversion was necessary in 7 cases (7.6%).
The benefits and safety of laparoscopic gastrectomy are evident, with similar outcomes to conventional surgery and all the advantages of minimally invasive access. The learning curve is long. Laparoscopic gastrectomy is a safe and effective option for the treatment of GC, avoiding nontherapeutic laparotomy in patients with advanced disease. Comparative prospective studies evaluating the long-term survival of these patients are still necessary.
胃癌手术旨在实现对原发肿瘤及其淋巴引流区域的切除,同时将对发病率和死亡率的不良影响降至最低,并尽可能提高生活质量。
1993年6月至2008年5月,我院对113例术前诊断为胃癌的患者考虑行腹腔镜胃切除术。男性居多,平均年龄为60岁。在进行腹腔检查后,使用腹腔镜超声确定是否存在肝深部转移。对于上三分之一和中三分之一的肿瘤,行全胃切除术及Roux-en-Y重建术;对于累及胃下三分之一的肿瘤,行毕罗Ⅱ式或Roux-en-Y重建术的胃次全切除术。两种情况均行D2淋巴结清扫术。
有21例(18.5%)因远处转移和/或侵犯相邻器官而无法切除肿瘤。在这些患者中,16例行腹腔镜活检,5例行腹腔镜胃空肠吻合术。92例患者接受了腹腔镜胃切除术,平均手术时间为162分钟,死亡率为5.4%。7例(7.6%)需要中转开腹。
腹腔镜胃切除术的益处和安全性是显而易见的,其结果与传统手术相似,且具有微创入路的所有优点。学习曲线较长。腹腔镜胃切除术是治疗胃癌的一种安全有效的选择,可避免对晚期疾病患者进行非治疗性剖腹手术。仍有必要进行比较性前瞻性研究以评估这些患者的长期生存情况。