Faculdade de Medicina de São José do Rio Preto, Rua Paraná 66, São José do Rio Preto, SP, Brazil.
Arq Bras Cardiol. 2009 Sep;93(3):307-11. doi: 10.1590/s0066-782x2009000900016.
Studies on hypermobility have aroused great interest in the last decades, as they are associated to musculoskeletal disorders, as well as abnormalities in several organic systems, such as the mitral valve prolapse. Therefore, in this study, data on the association between joint hypermobility and the mitral valve prolapse were investigated and reviewed. Studies in the literature have shown that genetic alterations in the collagen composition seem to be the main cause of this association.
过去几十年的研究表明，关节过度活动与肌肉骨骼疾病以及多个器官系统的异常有关，如二尖瓣脱垂。因此，本研究调查并回顾了关节过度活动与二尖瓣脱垂之间的关系。文献中的研究表明，胶原成分的遗传改变似乎是这种关联的主要原因。
