大鼠舌部电外科手术与冷刀的比较：一项初步实验研究。
Comparison between electrosurgery and cold blade in tongues of rats: a preliminary experimental study.
作者信息
Vasconcelos Belmiro Cavalcanti do Egito, Freitas Lígia Helena Macedo de, Santos Luciana Karla de Morais, Pereira José Ricardo Dias, Frota Riedel, Porto Gabriela Granja
机构信息
Department of Oral and Maxillofacial Surgery, PhD Program in Oral and Maxillofacial Surgery, UFPE, Recife, Brazil.
出版信息
Acta Cir Bras. 2009 Sep-Oct;24(5):362-6. doi: 10.1590/s0102-86502009000500005.
PURPOSE
To compare tissue cicatrization in the tongue of rats using electrosurgery and the cold blade.
METHODS
Ten adult male Wistar rats were divided into two groups of 5 animals each, according to the time of sacrifice (3 and 7 days). Each animal had two incisions, one made with a cold blade and the other with an electric blade, both of which were approximately 0.5 mm in length. Following sacrifice of the animals, the tongues were submitted to a histological study in order to classify the presence of angiogenesis, fibroblastic proliferation, epithelial proliferation and inflammatory cells as good, moderate and weak.
RESULTS
The wound made with electric blade presented a delay in the healing process and a greater inflammatory response as compared with the cold blade, despite the fact that there was no statistically significant difference (p<0.05).
CONCLUSION
There were no significant statistical differences between electrosurgery and the cold blade in relation to angiogenesis, fibroblastic proliferation, epithelial proliferation or the presence of inflammatory cells at any time of evaluation.
目的
比较使用电外科手术和冷刀在大鼠舌部造成的组织瘢痕形成情况。
方法
根据处死时间（3天和7天），将10只成年雄性Wistar大鼠分为两组，每组5只动物。每只动物有两个切口，一个用冷刀制作，另一个用电刀制作，两者长度均约为0.5毫米。处死动物后，对舌头进行组织学研究，以便将血管生成、成纤维细胞增殖、上皮细胞增殖和炎症细胞的存在情况分为良好、中等和较弱。
结果
与冷刀相比，电刀造成的伤口愈合过程延迟且炎症反应更大，尽管差异无统计学意义（p<0.05）。
结论
在任何评估时间点，电外科手术和冷刀在血管生成、成纤维细胞增殖、上皮细胞增殖或炎症细胞存在方面均无显著统计学差异。
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