Karadam Senem Yaman, Ertabaklar Hatice, Sari Cavide, Dayanir Yelda, Ertuğ Sema
Adnan Menderes Universitesi Tip Fakültesi, Parazitoloji Anabilim Dali, Aydin, Turkey.
Turkiye Parazitol Derg. 2009;33(3):203-6.
Cystic echinococcosis (CE) caused by the metacestode form of Echinococcus granulosus is one of the important health problems in Turkey and in the world. In this study, whether or not the presence of CE in patients with a high eosinophil count should be determined was investigated. A total of 946 specimens from patients with a high eosinophil count (>or=350/mm3) were evaluated. The age of patients ranged from 1-94 years. Of the patients, 392 (41.4%) were male and 554 (58.6%), female. The specific antibody response in the specimens was determined by ELISA and IHA. Specific antibody response was detected in five sera of 946 (0.53%) patients with ELISA and IHA. The patients, with an antibody response, were evaluated further with liver ultrasonography and chest X-ray. One patient, in which an antibody response was detected, had a history of renal cell carcinoma surgery. In one patient (0.11%), CE was detected in the liver and the diagnosis was confirmed by surgery. No CE was found in the other three patients. In conclusion, eosinophilia is not a sufficient indicator for CE alone and this parasite should be sought in patients with clinical and radiological signs.
由细粒棘球绦虫的中绦期幼虫引起的囊型包虫病（CE）是土耳其乃至全球重要的健康问题之一。在本研究中，调查了嗜酸性粒细胞计数高的患者是否应确定是否存在CE。共评估了946例嗜酸性粒细胞计数高（≥350/mm³）患者的标本。患者年龄范围为1至94岁。其中，男性392例（41.4%），女性554例（58.6%）。通过酶联免疫吸附测定（ELISA）和间接血凝试验（IHA）确定标本中的特异性抗体反应。在946例患者中的5例血清（0.53%）中通过ELISA和IHA检测到特异性抗体反应。对有抗体反应的患者进一步进行肝脏超声检查和胸部X线检查。1例检测到抗体反应的患者有肾细胞癌手术史。1例患者（0.11%）肝脏中检测到CE，手术确诊。其他3例患者未发现CE。总之，嗜酸性粒细胞增多症单独作为CE的指标并不充分，应在有临床和影像学体征的患者中寻找这种寄生虫。
