Division of Aging, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 3rd floor, Boston, MA 02120, USA.
Curr Atheroscler Rep. 2009 Nov;11(6):418-22. doi: 10.1007/s11883-009-0063-1.
Coronary heart disease (CHD) remains one of the leading causes of death in the United States and other industrialized nations. A better understanding of modifiable risk factors for CHD is critical in order to effectively prevent this disease. Dietary factors known to influence the risk of CHD include saturated fats, trans-fats, and polyunsaturated fatty acids. Although higher plasma levels of low-density lipoprotein cholesterol are associated with an increased risk of coronary disease and lipid-lowering therapy has been shown to reduce the risk of cardiovascular disease, the relation between dietary cholesterol and the risk of CHD is not clearly understood. This article reviews the current evidence on the association between dietary cholesterol and the risk of CHD.
冠心病（CHD）仍然是美国和其他工业化国家的主要死亡原因之一。为了有效地预防这种疾病，更好地了解冠心病的可改变危险因素至关重要。已知影响冠心病风险的饮食因素包括饱和脂肪、反式脂肪和多不饱和脂肪酸。虽然较高的血浆低密度脂蛋白胆固醇水平与冠心病风险增加有关，降脂治疗已被证明可降低心血管疾病的风险，但饮食胆固醇与冠心病风险之间的关系尚不清楚。本文综述了目前关于饮食胆固醇与冠心病风险之间关联的证据。
