采用沙利度胺成功治疗 Whipple 病的免疫重建炎症综合征。
Successful treatment of immune reconstitution inflammatory syndrome in Whipple's disease using thalidomide.
机构信息
Université de la Méditerranée, Unité des Rickettsies, URMITE CNRS-IRD UMR 6236, Faculté de Médecine, 27 Bd Jean Moulin, 13385 Marseille cedex 05, France.
出版信息
J Infect. 2010 Jan;60(1):79-82. doi: 10.1016/j.jinf.2009.09.017. Epub 2009 Oct 21.
PMID:19852981
Abstract
A patient with classic Whipple's disease developed erythema nodosum leprosum-like lesions and fever one month after the beginning of an accurate therapy with trimethoprim-sulfamethoxazole. Immune reconstitution inflammatory syndrome was suspected, but corticosteroid therapy failed to improve the patient. Finally, thalidomide was used and successfully induced rapid improvement.
摘要
一位患有典型惠普尔病的患者在开始使用甲氧苄啶-磺胺甲噁唑进行准确治疗一个月后出现了红斑狼疮样结节性皮损和发热。怀疑发生了免疫重建炎症综合征，但皮质类固醇治疗未能改善患者的病情。最终，使用了沙利度胺，并且成功地迅速改善了病情。
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