UNESP - São Paulo State University at Rio Claro, SP 13506-900, Brazil.
Gait Posture. 2010 Jan;31(1):143-6. doi: 10.1016/j.gaitpost.2009.09.011. Epub 2009 Oct 23.
The aim of this study was to compare the locomotor behavior of people with Parkinson's disease (PD) and healthy older adults during obstacle negotiation, both in the approaching and crossing phases. Twelve people with idiopathic PD, with mild to moderate disease, and 12 healthy individuals (CG) walked across an 8m pathway for three obstacle conditions: no obstacle, low obstacle and high obstacle. Each performed five trials for each obstacle condition. Performance was more disturbed for the high obstacle than the low obstacle. During the approach phase, people with PD demonstrated shorter stride length (F(1,22)=8.55, P=0.008) and greater stride duration (F(1,22)=7.371, P=0.013) than controls. Those with PD also increased their stance phase durations (F(1,22)=7.426, P=0.012) for both obstacle conditions, while the CG maintained comparable step durations for all conditions. For the crossing phase, people with PD demonstrated shorter step length (F(1,22)=9.699, P=0.005) over the obstacle. Leading limbs were closer to the obstacle, before and after crossing. Thus PD hypokinesia compromises the approach and crossing phases of obstacle negotiation.
本研究旨在比较帕金森病（PD）患者和健康老年人在接近和穿越障碍物阶段的运动行为。12 名特发性 PD 患者，病情从中度到轻度，以及 12 名健康个体（CG）在 8m 通道上行走，有三种障碍物条件：无障碍物、低障碍物和高障碍物。每个人对每种障碍物条件进行五次试验。高障碍物的表现比低障碍物更差。在接近阶段，PD 患者的步幅长度（F(1,22)=8.55，P=0.008）和步幅持续时间（F(1,22)=7.371，P=0.013）均短于对照组。PD 患者在两种障碍物条件下还增加了支撑相时长（F(1,22)=7.426，P=0.012），而 CG 在所有条件下都保持了相似的步幅时长。在穿越阶段，PD 患者跨越障碍物时的步长更短（F(1,22)=9.699，P=0.005）。穿越前和穿越后，主导肢体更靠近障碍物。因此，PD 运动减少会影响障碍物协商的接近和穿越阶段。
