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甲型H1N1流感病毒所致肺炎及急性呼吸窘迫综合征

[Pneumonia and the acute respiratory distress syndrome due to influenza A (H1N1) virus].

作者信息

López C de Haro, Roca R Ferrer, Daunis J Vallés

机构信息

Centro de Críticos, Hospital de Sabadell, CIBER Enfermedades Respiratorias, Instituto Universitario Parc Tauli, Universidad Autónoma de Barcelona, España.

出版信息

Med Intensiva. 2009 Dec;33(9):455-8. doi: 10.1016/j.medin.2009.09.004. Epub 2009 Oct 25.

Abstract

The acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are part of a devastating syndrome characterized by acute onset, hypoxemia, and bilateral infiltrates on chest x-rays. ALI/ARDS is the response of the lung to a local or systemic aggression, resulting in local inflammation and coagulation disorders, which lead to increased inflammatory pulmonary edema. ARDS is a major cause of morbidity, death, and cost in intensive care units. The most common cause is sepsis. We present a case of ARDS secondary to infection with the influenza A (H1N1) virus. The influenza A (H1N1) virus caused a global pandemia 91 years ago, with sporadic outbreaks afterward. The new influenza A pandemia was transmitted from swine to humans. Infection by the influenza A (H1N1) virus can cause severe respiratory illness, the acute respiratory distress syndrome, and secondary infections among healthcare workers.

摘要

急性呼吸窘迫综合征(ARDS)和急性肺损伤(ALI)是一种严重综合征的一部分,其特征为急性起病、低氧血症以及胸部X光片显示双侧浸润影。ALI/ARDS是肺部对局部或全身侵袭的反应,导致局部炎症和凝血功能障碍,进而引起炎性肺水肿加重。ARDS是重症监护病房发病、死亡和医疗费用的主要原因。最常见的病因是脓毒症。我们报告一例甲型H1N1流感病毒感染继发ARDS的病例。91年前甲型H1N1流感病毒引发了全球大流行,此后有散发病例。此次新的甲型流感大流行是由猪传播给人类的。甲型H1N1流感病毒感染可导致严重的呼吸系统疾病、急性呼吸窘迫综合征以及医护人员的继发感染。

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