每日短信提醒可提高哮喘治疗的依从性：一项为期三个月的随访研究。
A daily SMS reminder increases adherence to asthma treatment: a three-month follow-up study.
机构信息
Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen NV, Denmark.
出版信息
Respir Med. 2010 Feb;104(2):166-71. doi: 10.1016/j.rmed.2009.10.003. Epub 2009 Oct 25.
BACKGROUND
Poor adherence to asthma treatment is a well-recognised challenge and is associated with increased morbidity, mortality and consumption of health care resources. This study examined the impact of receiving a daily text message reminder on one's cell phone on adherence to asthma treatment.
METHODS
A total of 26 subjects aged 18-45 years, with a clinical history of asthma and a positive methacholine challenge test (PD(20)<or=4micromol) were randomised to receive, or to not receive, a daily short message service (SMS) reminder on their cell phone to take their anti-asthmatic medication. Inhaled corticosteroids to last for eight weeks and a prescription for four additional weeks were given to the subjects. The primary outcome was adherence to asthma treatment. Secondary outcomes were reimbursement of asthma medication, and change in exhaled nitric oxide levels, lung function, and airway responsiveness.
RESULTS
The absolute difference in mean adherence rate between the two groups after 12 weeks was 17.8%, 95% CI (3.2-32.3%), p=0.019. No significant differences were observed between the two randomisation groups for the secondary outcomes.
CONCLUSION
Daily text message reminders are already after a short period of observation associated with increased adherence to anti-asthmatic medication.
背景
哮喘治疗的依从性差是一个众所周知的挑战，与发病率、死亡率的增加以及医疗资源的消耗有关。本研究考察了每天在手机上收到短信提醒对哮喘治疗依从性的影响。
方法
共纳入 26 名年龄在 18-45 岁之间、有哮喘临床病史和阳性乙酰甲胆碱激发试验（PD(20)<或=4μm）的受试者，随机分为接受或不接受每天的手机短信提醒以服用他们的哮喘药物。给予受试者吸入性皮质激素持续 8 周，并开具了额外 4 周的处方。主要结局是哮喘治疗的依从性。次要结局是哮喘药物的报销情况以及呼气一氧化氮水平、肺功能和气道反应性的变化。
结果
12 周后，两组间平均依从率的绝对差异为 17.8%，95%可信区间（3.2-32.3%），p=0.019。两组在次要结局方面没有观察到显著差异。
结论
即使在短时间观察期内，每天的短信提醒也与增加抗哮喘药物的依从性相关。
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