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一名艾滋病患者在接受抗逆转录病毒治疗期间发生肺堪萨斯分枝杆菌感染导致免疫重建炎症综合征。

An AIDS patient with immune reconstitution inflammatory syndrome due to pulmonary Mycobacterium kansasii infection during antiretroviral therapy.

机构信息

Department of Pulmonary and Infectious Diseases, Shinshu University Hospital, Matsumoto, Japan.

出版信息

J Infect Chemother. 2009 Oct;15(5):331-4. doi: 10.1007/s10156-009-0711-y. Epub 2009 Oct 24.

Abstract

After the recovery of pneumocystis pneumonia, amebiasis, and cytomegalovirus duodenal ulcer in a patient with AIDS, antiretroviral therapy was initiated. Fever was first noted on the 11th day of administration of the highly active antiretroviral therapy (HAART), and chest radiography showed infiltration into the right lower lobe of the lung on the 19th day. Bronchoscopy was performed, with a tentative diagnosis of pulmonary tuberculosis, but Mycobacterium kansasii was eventually identified. M. kansasii may also be a pathogenic organism causing immune reconstitution inflammatory syndrome.

摘要

患者 AIDS 并发肺孢子菌肺炎、阿米巴病和巨细胞病毒十二指肠溃疡痊愈后,开始接受抗反转录病毒治疗。第 11 天给药时首次出现发热,第 19 天胸部 X 线检查显示右下肺浸润。进行支气管镜检查,暂诊断为肺结核,但最终鉴定为堪萨斯分枝杆菌。堪萨斯分枝杆菌也可能是引起免疫重建炎症综合征的致病病原体。

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