Department of Chemistry, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada.
Org Lett. 2009 Nov 19;11(22):5346-9. doi: 10.1021/ol902216y.
Herein, we describe enantioselective addition of alkenyltin reagents possessing a reactive and sensitive allylic functionality not readily available to other classes of alkenyl metals. This method is enabled by the use of highly electrophilic alkylidene Meldrum's acids as acceptors and a cationic Rh(I)-diene complex as catalyst.
在此，我们描述了具有反应性和敏感性烯丙基官能团的烯基锡试剂的对映选择性加成，而其他烯属金属则不易获得此类官能团。该方法的实现得益于使用高亲电性的亚甲基 Meldrum's 酸作为受体和阳离子 Rh(I)-二烯络合物作为催化剂。
