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[射频消融术治疗肝脏和肺部肿瘤]

[Radiofrequency ablation in the treatment of liver and lung tumors].

作者信息

Palussière J, Descat E, Fonck M, Bonichon F, Chomy F, Bécouarn Y, Avril A, Kind M, Ravaud A

机构信息

Départements de radiologie, Institut Bergonié, Centre régional de lutte contre le cancer, 229, cours de l'Argonne, 33076 Bordeaux cedex, France.

出版信息

Bull Cancer. 2009 Nov;96(11):1099-109. doi: 10.1684/bdc.2009.0974.

DOI:10.1684/bdc.2009.0974
PMID:19858044
Abstract

Radiofrequency (RF) ablation is a technique of thermotherapy which emerged over the last fifteen years in the field of oncology. RF directed toward a specific tumor mass is known to be very effective (over 90%) for treating tumors less than 2.5 cm. RF is used for patients with early-stage lung or liver cancers who are not surgical candidates, With improvements in systemic therapy, increasing interest in the use of local therapy for metastases has arisen. Eradication of residual metastases via local therapies has a sense in patients with stabilized disease. Nonsurgical alternative like RF has become popular because it is less invasive than surgery and has demonstrated great efficiency. Nevertheless prospective randomized trials to compare RF with surgery are difficult to achieve, prospective studies are needed to better evaluate the technique.

摘要

射频(RF)消融是一种热疗技术,在过去十五年中出现在肿瘤学领域。已知针对特定肿瘤块的射频对于治疗小于2.5厘米的肿瘤非常有效(超过90%)。射频用于那些不适合手术的早期肺癌或肝癌患者。随着全身治疗的改进,人们对使用局部治疗来处理转移瘤的兴趣日益增加。对于病情稳定的患者,通过局部治疗根除残留转移瘤是有意义的。像射频这样的非手术替代方法已变得流行,因为它比手术侵入性小且已显示出很高的效率。然而,将射频与手术进行比较的前瞻性随机试验很难开展,需要进行前瞻性研究以更好地评估该技术。

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