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[介入放射学方法在骨转移瘤治疗中的应用]

[Interventional radiology procedures in the treatment of bone metastasis].

作者信息

Palussière Jean, Dixmerias Florence, Buy Xavier, Descat Edouard, Bonichon Françoise, Debled Marc, Pointillart Vincent, Gangi Afshin

机构信息

Départements d'imagerie, centre régional de lutte contre cancer, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux cedex, France.

出版信息

Bull Cancer. 2009 Nov;96(11):1117-26. doi: 10.1684/bdc.2009.0973.

Abstract

Over the last ten years, there has been much development in the treatment of bone metastases using percutaneous image-guided interventional radiology procedures. They are helpful in the management of patients resulting in stabilization of bone lysis in order to achieve additional biomechanical stability and in significant symptomatic relief. Vertebroplasty consisting in an injection of an acrylic cement into a structurally weakened or destructed bone plays a major role in the management of specific bone weakening. Advances have been made also with the application of thermoablation procedures to bone tumors (radiofrequency ablation, cryotherapy). Since conservative treatment with analgesics is often insufficient and the analgesic effect of radiation therapy is delayed and sometimes ineffective, these image-guided procedures play a beneficial role in the management of bone metastases and need more evaluation.

摘要

在过去十年中,经皮图像引导介入放射学程序在骨转移瘤治疗方面取得了很大进展。它们有助于患者的管理,可稳定骨质溶解,以实现额外的生物力学稳定性,并显著缓解症状。椎体成形术是将丙烯酸骨水泥注入结构薄弱或破坏的骨骼中,在特定骨质薄弱的管理中发挥着重要作用。热消融程序(射频消融、冷冻疗法)应用于骨肿瘤也取得了进展。由于使用镇痛药的保守治疗往往不足,且放射治疗的镇痛效果延迟且有时无效,这些图像引导程序在骨转移瘤的管理中发挥着有益作用,需要更多评估。

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