Sansone Randy A, Wiederman Michael W
Wright State University and Kettering Medical Center, Ohio, USA.
Int J Psychiatry Med. 2009;39(2):147-54. doi: 10.2190/PM.39.2.c.
In this study, the prevalence of prescription substance abuse among those with borderline personality symptomatology was examined in a large cohort of respondents who participated in one of 13 prior research projects.
The entire cohort (N = 1039) was divided into 3 subsamples: a psychiatric sample (n = 440), a predominantly primary care sample (n = 599), and an internal medicine sample (n = 332; i.e., a well-defined subset of the predominantly primary care sample that consisted of only internal medicine outpatients seen at one location). The borderline personality scale of the Personality Diagnostic Questionnaire (PDQ), either the revised (PDQ-R) or fourth (PDQ-4) version, was used to diagnose all participants either with or without borderline personality. One item from the Self-Harm Inventory, "Have you ever intentionally, or on purpose, abused prescription medication?," was then used in the subsequent analyses.
Among the psychiatric, predominantly primary care, and internal medicine subsamples, the prevalence rates of prescription medication abuse in those diagnosed with borderline personality according to the PDQ were 46.9%, 46.2%, and 11.5%, respectively. In all subsamples, those with borderline personality were statistically significantly more likely to abuse prescription medication than those without the disorder. For example, borderline patients in the psychiatric sample were twice as likely to abuse prescription medications, in the predominantly primary care sample 4 times as likely, and in the internal medicine only sample nearly 6 times as likely.
Regardless of setting, patients with BPD are at great risk for the abuse of prescription medications.
在本研究中,对参与之前13个研究项目之一的一大群受访者进行调查,以探究边缘型人格症状患者中处方药物滥用的患病率。
整个队列(N = 1039)被分为3个子样本:一个精神科样本(n = 440)、一个以初级保健为主的样本(n = 599)和一个内科样本(n = 332;即仅由在一个地点就诊的内科门诊患者组成的、以初级保健为主的样本中的一个明确子集)。使用人格诊断问卷(PDQ)的边缘型人格量表,即修订版(PDQ - R)或第四版(PDQ - 4),对所有参与者进行边缘型人格诊断,无论其是否患有该人格障碍。随后的分析使用了自伤量表中的一个项目:“你是否曾经故意滥用处方药?”
在精神科、以初级保健为主和内科子样本中,根据PDQ诊断为边缘型人格的患者中,处方药物滥用的患病率分别为46.9%、46.2%和11.5%。在所有子样本中,边缘型人格患者滥用处方药的可能性在统计学上显著高于非边缘型人格障碍患者。例如,精神科样本中的边缘型患者滥用处方药的可能性是其他患者的两倍,在以初级保健为主的样本中是4倍,在内科样本中则接近6倍。
无论在哪种环境下,边缘型人格障碍患者都面临着滥用处方药的巨大风险。