Psychosis poses a major challenge for natural selection. The heritability of psychotic disorders is considerable and psychosis is associated with decreased reproductive success. Natural selection has not succeeded in eliminating the genes that predispose to the illness. Yet natural selection is considered to prune those features that decrease reproductive success. This paper deals with various evolutionary psychiatric models of major psychoses. According to Burns's model it is argued that psychosis may be the high price that humans have to pay for the evolution of their complex social brains. The same genes that have helped to shape our humanity carry the risk of psychosis. As such the genes would confer an evolutionary advantage, but their incremental effect would increase the risk of psychosis.
精神病对自然选择构成了重大挑战。精神障碍具有相当高的遗传性,且精神病与生殖成功率降低有关。自然选择未能成功消除那些易患该疾病的基因。然而,自然选择被认为会淘汰那些降低生殖成功率的特征。本文探讨了主要精神病的各种进化精神病学模型。根据伯恩斯的模型,有人认为精神病可能是人类为其复杂社会大脑的进化所必须付出的高昂代价。那些有助于塑造我们人性的相同基因也带来了患精神病的风险。因此,这些基因会带来进化优势,但其累加效应会增加患精神病的风险。