Rega Paul, Burkholder-Allen Kelly, Bork Christopher
Department of Public Health and Preventive Medicine, College of Medicine, University of Toledo, Toledo, Ohio, USA.
Am J Disaster Med. 2009 Jul-Aug;4(4):192-8.
Botulinum toxin is one of the most toxic substances known to humankind. It is one among the six Category A agents in the CDC bioterrorism lexicon. This suggests that, while the possibility of a botulism mass casualty incident (MCI) is remote, its unique acute and long-term ramifications must be addressed and planned for. However, an in-depth knowledge of the disease and its tactical management in the acute MCI phase is inconsistent or superficial among healthcare personnel. Therefore, an algorithm has been developed to assist first receivers with the initial management of multiple probable and potential botulism patients when equipment resources are strained and when expert personnel are not readily available. The algorithm is specifically structured to assist with the identification and management of potential respiratory deterioration of suspected botulism patients.
肉毒杆菌毒素是人类已知的毒性最强的物质之一。它是美国疾病控制与预防中心（CDC）生物恐怖主义词汇表中的六种A类制剂之一。这表明，虽然肉毒中毒大规模伤亡事件（MCI）的可能性很小，但其独特的急性和长期影响必须得到应对和规划。然而，医护人员对该疾病及其在急性MCI阶段的战术管理的深入了解并不一致或很肤浅。因此，已经开发了一种算法，以在设备资源紧张且专家人员难以随时获取时，协助首批接收者对多名可能和潜在的肉毒中毒患者进行初始管理。该算法的具体结构旨在协助识别和管理疑似肉毒中毒患者潜在的呼吸功能恶化情况。
