Kato T, Takahashi S, Kikugawa K
Tokyo College of Pharmacy, Japan.
Mutat Res. 1991 Jan;246(1):169-78. doi: 10.1016/0027-5107(91)90119-9.
The presence of 2 kinds of components in brewed and instant coffee that could remove and destroy heterocyclic amine mutagens was demonstrated. The component that could remove the mutagens was insoluble fiber composed of hemicellulose. The fiber could tightly adsorb the mutagens Trp-P-1, Trp-P-2, Glu-P-1 and A alpha C, and those generated in roasted coffee beans. The component that could destroy the mutagens was high-molecular-weight soluble polyphenolics. They might be converted into quinone derivatives in the presence of molecular oxygen. The quinone derivatives might destroy the mutagens. The fibers and the polyphenolics in one cup of brewed or instant coffee had the capacity to remove and destroy a substantial amount of the mutagens in pyrolysates of foodstuffs.
研究表明，冲泡咖啡和速溶咖啡中存在两种能够去除和破坏杂环胺诱变剂的成分。能够去除诱变剂的成分是由半纤维素组成的不溶性纤维。这种纤维能够紧密吸附诱变剂Trp-P-1、Trp-P-2、Glu-P-1和AαC，以及烘焙咖啡豆中产生的诱变剂。能够破坏诱变剂的成分是高分子量可溶性多酚。在分子氧存在的情况下，它们可能会转化为醌衍生物。醌衍生物可能会破坏诱变剂。一杯冲泡咖啡或速溶咖啡中的纤维和多酚具有去除和破坏大量食品热解产物中诱变剂的能力。
