Fedele D A, Mullins L L, Eddington A R, Ryan J L, Junghans A N, Hullmann S E
Department of Psychology, Oklahoma State University, Stillwater, Oklahoma 74078, USA.
J Asthma. 2009 Oct;46(8):835-40.
The current study investigated whether differences existed in health-related quality of life between individuals who self-identified as having childhood-onset asthma and individuals without a chronic illness. Additionally, the relationship between perceived illness intrusiveness and illness uncertainty to health-related quality of life was explored.
College undergraduates at least 18 years of age who self-identified as having childhood asthma were randomly matched by age and gender to healthy control participants. Participants completed a demographic form, the Mishel Uncertainty in Illness Scale-Community Form, the Illness Intrusiveness Scale, and the SF-36 Health Survey, a measure of health-related quality of life.
Participants with asthma had significantly lower scores on the total and mental health-related quality of life scales than did healthy control subjects. There were no significant differences between self-identified participants with asthma and matched healthy control subjects on physical health-related quality of life scales. Illness intrusiveness was not related to either the physical (e.g., physical functioning, general health) or mental health-related quality of life. Higher levels of illness uncertainty were significantly related to higher levels of mental health-related quality of life (e.g., vitality, mental health). In addition, participants with asthma scored significantly lower than healthy controls on the social functioning and role-emotional subscales.
The current study adds to the extant literature by examining the relationships between illness intrusiveness, illness uncertainty, and health-related quality of life among a young adult population. College students with asthma appear to be at risk for diminished quality of life compared to a healthy comparison group. Further examination of various domains of health-related quality of life among older adolescents and young adults with childhood asthma is needed.
本研究调查了自我认定患有儿童期哮喘的个体与无慢性病个体在健康相关生活质量方面是否存在差异。此外，还探讨了疾病侵扰感和疾病不确定性与健康相关生活质量之间的关系。
年龄至少18岁且自我认定患有儿童期哮喘的大学生按年龄和性别与健康对照参与者进行随机匹配。参与者完成一份人口统计学表格、米舍尔疾病不确定感量表社区版、疾病侵扰量表以及SF - 36健康调查，后者是一种健康相关生活质量的测量工具。
哮喘患者在总体和心理健康相关生活质量量表上的得分显著低于健康对照者。在身体健康相关生活质量量表上，自我认定的哮喘患者与匹配的健康对照者之间没有显著差异。疾病侵扰与身体（如身体功能、总体健康）或心理健康相关生活质量均无关。更高水平的疾病不确定性与更高水平的心理健康相关生活质量（如活力、心理健康）显著相关。此外，哮喘患者在社会功能和角色情感子量表上的得分显著低于健康对照者。
本研究通过考察年轻成年人群中疾病侵扰、疾病不确定性与健康相关生活质量之间的关系，为现有文献增添了内容。与健康对照组相比，患有哮喘的大学生似乎存在生活质量下降的风险。需要进一步研究患有儿童期哮喘的青少年和年轻成年人在健康相关生活质量的各个领域的情况。
