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Chemical reversal of the RNA gain of function in myotonic dystrophy.

作者信息

Cooper Thomas A

机构信息

Department of Pathology and Molecular, Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18433-4. doi: 10.1073/pnas.0910643106. Epub 2009 Oct 28.

Abstract
摘要

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本文引用的文献

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PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1.
J Clin Invest. 2009 Dec;119(12):3797-806. doi: 10.1172/JCI37976. Epub 2009 Nov 9.
2
Pentamidine reverses the splicing defects associated with myotonic dystrophy.
Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18551-6. doi: 10.1073/pnas.0903234106. Epub 2009 Oct 12.
3
A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding.
Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16068-73. doi: 10.1073/pnas.0901824106. Epub 2009 Sep 8.
4
Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy.
Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13915-20. doi: 10.1073/pnas.0905780106. Epub 2009 Aug 10.
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Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA.
Science. 2009 Jul 17;325(5938):336-9. doi: 10.1126/science.1173110.
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RNA and disease.
Cell. 2009 Feb 20;136(4):777-93. doi: 10.1016/j.cell.2009.02.011.

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