DiPalma J R
Hahnemann University School of Medicine, Philadelphia, Pennsylvania.
Am Fam Physician. 1991 Jan;43(1):207-10.
Ketorolac tromethamine is the first injectable nonsteroidal anti-inflammatory drug approved for the management of acute pain. In analgesic potency and ability to relieve postoperative pain, it is comparable to morphine. The advantages of ketorolac over opiates are the absence of respiratory depression and lack of drug abuse potential. Ketorolac has a longer duration of action than morphine, but it has less effect on the central nervous system. Ketorolac should not be used for obstetric analgesia.
酮咯酸氨丁三醇是首个被批准用于管理急性疼痛的注射用非甾体抗炎药。在镇痛效力和缓解术后疼痛的能力方面，它与吗啡相当。酮咯酸相对于阿片类药物的优势在于不存在呼吸抑制且无药物滥用潜力。酮咯酸的作用持续时间比吗啡长，但对中枢神经系统的影响较小。酮咯酸不应被用于产科镇痛。
