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L细胞中脂质积累的来源。

THE SOURCE OF LIPID ACCUMULATION IN L CELLS.

作者信息

Bensch K G, King D W, Socolow E L

机构信息

Department of Pathology, Yale University School of Medicine, New Haven.

出版信息

J Biophys Biochem Cytol. 1961 Jan 1;9(1):135-9. doi: 10.1083/jcb.9.1.135.

Abstract

Strain L cells accumulate lipid, concurrent with cessation of protein synthesis, in the stationary phase of growth from the extracellular medium and as a result of de novo synthesis. Cells which have been more severely damaged with an amino acid analogue also accumulate lipid from the extracellular medium, but synthesize very little lipid from labeled acetate. The possible roles which lipid accumulation may play in the cell are discussed.

摘要

L 菌株在生长的稳定期从细胞外培养基中积累脂质,同时蛋白质合成停止,这是从头合成的结果。用氨基酸类似物严重损伤的细胞也从细胞外培养基中积累脂质,但从标记的乙酸盐合成的脂质很少。本文讨论了脂质积累在细胞中可能发挥的作用。

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