Medical Service of the Massachusetts General Hospital, Boston.
J Exp Med. 1916 Dec 1;24(6):671-81. doi: 10.1084/jem.24.6.671.
It may be said that at rest all the factors of respiration, gaseous exchange, carbon dioxide tension, and the mechanical factors, are normal in persons with a collapsed lung, that the reaction to carbon dioxide is normal up to the point at which the respiration is trebled, or sometimes quadrupled, but that beyond that point a limit may be reached. The ventilation of the lungs can be accomplished in an entirely normal manner in spite of a greatly reduced vital capacity. The only difference between normal persons and persons with a collapsed lung is that the latter when called upon to increase their ventilation reach their limit a little sooner than the former. From these findings we might deduce that there will be no dyspnea except after moderate exertion. And this deduction is borne out by the histories of the patients. In other words, in the lungs, as in other organs, there is a large factor of safety, one lung being as efficient as two, except when the work done calls for more than a threefold increase in the normal ventilation.
可以说,在休息时,所有呼吸因素、气体交换、二氧化碳张力和机械因素在肺萎陷的人中都是正常的,对二氧化碳的反应在呼吸增加三倍或有时四倍之前是正常的,但在此之后可能达到极限。尽管肺活量大大降低,但肺部的通气仍可以以完全正常的方式完成。正常人和肺萎陷的人唯一的区别是,后者在需要增加通气时,比前者更早达到极限。从这些发现中,我们可以推断,除了适度运动外,不会出现呼吸困难。而且,这一推论得到了患者病史的证实。换句话说,就像在其他器官一样,肺部也有很大的安全系数,一个肺的效率与两个肺相同,除非所做的工作需要正常通气增加三倍以上。